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1

Preparation of 2-deoxystreptamine derivatives with all-axial substituents for desymmetrization

Yue-Lei Chen, Jutta Pyplo-Schnieders, Hartmut Redlich, Heinrich Luftmann, Roland Fröhlich

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 167 KB

english, 2007

2

Fragment-Based Drug Discovery of 2-Thiazolidinones as BRD4 Inhibitors: 2. Structure-Based Optimization

Zhao, Lele, Wang, Yingqing, Cao, Danyan, Chen, Tiantian, Wang, Qi, Li, Yanlian, Xu, Yechun, Zhang, Naixia, Wang, Xin, Chen, Danqi, Chen, Lin, Chen, Yue-Lei, Xia, Guangxin, Shi, Zhe, Liu, Yu-Chih, Lin,

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 972 KB

english, 2015

3

A Facile One-Pot Synthesis of N4-Alkyloxycarbonyl Cytosine Nucleosides.

Yue-Lei Chen, Jun-Da Cen

Journal:

Year:

2005

File:

PDF, 15 KB

2005

4

Sorafenib inhibits transforming growth factor β1-Mediated Epithelial-Mesenchymal Transition and apoptosis in mouse hepatocytes

Yue-Lei Chen, Jing Lv, Xiao-Lei Ye, Ming-Yu Sun, Qin Xu, Cheng-Hai Liu, Li-Hua Min, Hui-Ping Li, Ping Liu, Xiaoyan Ding

Journal:

Year:

2011

Language:

english

File:

PDF, 707 KB

english, 2011

5

Copper-catalyzed asymmetric addition of Et2Zn to 2-cyclohexen-1-one and 2-carbamoyloxy-2-cyclohexen-1-one with phosphoramidite, phosphite, and bidentate phosphite–oxazoline ligands

Yue-Lei Chen, Roland Fröhlich, Dieter Hoppe

Journal:

Tetrahedron: Asymmetry

Year:

2009

Language:

english

File:

PDF, 370 KB

english, 2009

6

Copper-catalyzed asymmetric conjugate addition of Grignard reagents to 1-(N,N-diisopropylcarbamoyloxy)-1-tosyl-1-alkenes

Yue-Lei Chen, Dieter Hoppe

Journal:

Tetrahedron: Asymmetry

Year:

2009

Language:

english

File:

PDF, 553 KB

english, 2009

7

Production of bacterial blight resistant lines from somatic hybridization betweenOryza sativaL. andOryza meyerianaL.

Cheng-qi Yan, Kai-xian Qian, Gang-ping Xue, Zhong-chang Wu, Yue-lei Chen, Qiu-sheng Yan, Xue-qing Zhang, Ping Wu

Journal:

Journal of Zhejiang University SCIENCE A

Year:

2004

Language:

english

File:

PDF, 1.38 MB

english, 2004

8

The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus

Yue-Lei Chen, Jing Tang, Matthew J. Kesler, Yuk Y. Sham, Robert Vince, Robert J. Geraghty, Zhengqiang Wang

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 2.11 MB

english, 2012

9

P4-ATPase ATP8A2 acts in synergy with CDC50A to enhance neurite outgrowth

Qin Xu, Guo-Ying Yang, Na Liu, Peng Xu, Yue-Lei Chen, Zheng Zhou, Zhen-Ge Luo, Xiaoyan Ding

Journal:

Year:

2012

Language:

english

File:

PDF, 1.42 MB

english, 2012

10

The role of Paraxial Protocadherin in Xenopus otic placode development

Rui-Ying Hu, Peng Xu, Yue-Lei Chen, Xin Lou, Xiaoyan Ding

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 2.21 MB

english, 2006

11

C-6 aryl substituted 4-quinolone-3-carboxylic acids as inhibitors of hepatitis C virus

Yue-Lei Chen, Jeana Zacharias, Robert Vince, Robert J. Geraghty, Zhengqiang Wang

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 2.80 MB

english, 2012

12

(N,N-Diisopropylcarbamoyloxy)-methyl p-tolyl sulfone: preparation and application for the syntheses of 1,2-diols

Lu Ma, Dongmei Zhao, Lin Chen, Xin Wang, Yue-Lei Chen, Jingkang Shen

Journal:

Year:

2012

Language:

english

File:

PDF, 867 KB

english, 2012

13

Time-dependent magnetoelectric effect in Fe/Pb(Mg1/3Nb2/3)0.7Ti0.3O3 heterostructure: A ferromagnetic resonance study

Zhao, Yue-Lei, Chen, Qian-Ping, Zhao, Yong-Gang, Pan, Liqing, Sun, Young

Journal:

Applied Physics Letters

Year:

2013

Language:

english

File:

PDF, 675 KB

english, 2013

14

Direct Glycosylation of Bioactive Small Molecules with Glycosyl Iodide and Strained Olefin as Acid Scavenger

Gu, Xiangying, Chen, Lin, Wang, Xin, Liu, Xiao, You, Qidong, Xi, Wenwei, Gao, Li, Chen, Guohua, Chen, Yue-Lei, Xiong, Bing, Shen, Jingkang

Journal:

Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 627 KB

english, 2014

15

1,2-trans-1-Dihydroxyboryl benzyl S-glycoside as glycosyl donor

Liu, Xiao, Zhang, Bingbing, Gu, Xiangying, Chen, Guohua, Chen, Lin, Wang, Xin, Xiong, Bing, You, Qi-Dong, Chen, Yue-Lei, Shen, Jingkang

Journal:

Carbohydrate Research

Year:

2014

Language:

english

File:

PDF, 808 KB

english, 2014

16

Highly Stereoselective Nucleophilic Addition of Difluoromethyl-2-pyridyl Sulfone to Sugar Lactones and Efficient Synthesis of Fluorinated 2-Ketoses

Liu, Xiao, Yin, Qiang, Yin, Jian, Chen, Guohua, Wang, Xin, You, Qi-Dong, Chen, Yue-Lei, Xiong, Bing, Shen, Jingkang

Journal:

European Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 435 KB

english, 2014

17

Synthesis and bioassay of β-(1,4)-D-mannans as potential agents against Alzheimer's disease

Jiang, Ru-wei, Du, Xiao-guang, Zhang, Xuan, Wang, Xin, Hu, Ding-yu, Meng, Tao, Chen, Yue-lei, Geng, Mei-yu, Shen, Jing-kang

Journal:

Acta Pharmacologica Sinica

Year:

2013

Language:

english

File:

PDF, 504 KB

english, 2013

18

1-( N,N -Diisopropylcarbamoyloxy)-1-tosyl-1-alkenes— a 2d 1 Synthons via Tandem Umpolung

Chen, Yue-Lei, Hoppe, Dieter

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 213 KB

english, 2009

19

Condensed Fukui function predicts innate C–H radical functionalization sites on multi-nitrogen containing fused arenes

Ma, Yuchi, Liang, Jin, Zhao, Dongmei, Chen, Yue-Lei, Shen, Jingkang, Xiong, Bing

Journal:

Year:

2014

Language:

english

File:

PDF, 343 KB

english, 2014

20

d-Glucosamine trimethylene dithioacetal derivatives: formation of six- and seven-membered ring amino carbasugars. Synthesis of (–)-calystegine B3,

Chen, Yue-Lei, Redlich, Hartmut, Bergander, Klaus, Fröhlich, Roland

Journal:

Organic & Biomolecular Chemistry

Year:

2007

Language:

english

File:

PDF, 259 KB

english, 2007

21

Strained olefin enables triflic anhydride mediated direct dehydrative glycosylation

Chen, Guohua, Yin, Qiang, Yin, Jian, Gu, Xiangying, Liu, Xiao, You, Qidong, Chen, Yue-Lei, Xiong, Bing, Shen, Jingkang

Journal:

Organic & Biomolecular Chemistry

Year:

2014

Language:

english

File:

PDF, 634 KB

english, 2014

22

Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke–Blackburn–Bienaymé reaction and their Hsp90 inhibitory activity

Ren, Jing, Yang, Min, Liu, Hongchun, Cao, Danyan, Chen, Danqi, Li, Jian, Tang, Le, He, Jianhua, Chen, Yue-Lei, Geng, Meiyu, Xiong, Bing, Shen, Jingkang

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 1.70 MB

english, 2015

23

Design and Optimization of a Series of 1-Sulfonylpyrazolo[4,3- b ]pyridines as Selective c-Met Inhibitors

Ma, Yuchi, Sun, Guangqiang, Chen, Danqi, Peng, Xia, Chen, Yue-Lei, Su, Yi, Ji, Yinchun, Liang, Jin, Wang, Xin, Chen, Lin, Ding, Jian, Xiong, Bing, Ai, Jing, Geng, Meiyu, Shen, Jingkang

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.74 MB

english, 2015

24

Trimethylene Dithioacetals of Carbohydrates, Part 6: C-C Coupling Reactions of Dilithiated N -Acetyl- d -glucosamine Trimethylene Dithioacetal Derivatives

Chen, Yue-Lei, Leguijt, Robin, Redlich, Hartmut, Fröhlich, Roland

Journal:

Year:

2006

Language:

english

File:

PDF, 212 KB

english, 2006

25

Energetic factors determining the binding of type I inhibitors to c-Met kinase: experimental studies and quantum mechanical calculations

Yu, Zhe, Ma, Yu-chi, Ai, Jing, Chen, Dan-qi, Zhao, Dong-mei, Wang, Xin, Chen, Yue-lei, Geng, Mei-yu, Xiong, Bing, Cheng, Mao-sheng, Shen, Jing-kang

Journal:

Acta Pharmacologica Sinica

Year:

2013

Language:

english

File:

PDF, 890 KB

english, 2013

26

Propane-1,3-diyl Dithioacetals of Carbohydrates; Part 7: Preparation of Aminocyclitols and Iminosugars by Intramolecular Cyclizations of d -Glucosamine Propane-1,3-diyl Dithioacetal Derivatives

Chen, Yue-Lei, Leguijt, Robin, Redlich, Hartmut

Journal:

Year:

2006

Language:

english

File:

PDF, 181 KB

english, 2006

27

Formation of 1,3-diazocine by palladium catalyzed C–H arylation

Tang, Le, Ren, Jing, Ma, Yuchi, Wang, Xin, Chen, Lin, Shen, Jingkang, Chen, Yue-Lei, Xiong, Bing

Journal:

Tetrahedron Letters

Year:

2016

Language:

english

File:

PDF, 1.41 MB

english, 2016

28

Transcriptomic analyses of nitrogen assimilation processes in a Chinese strain of Aureococcus anophagefferens

Chen, Li-Na, Dong, Hong-Po, Huang, Kai-Xuan, Wang, Hua-Long, Lu, Song-Hui, Cen, Jing-Yi, Dong, Yue-Lei

Journal:

Year:

2015

Language:

english

File:

PDF, 166 KB

english, 2015

29

Sorafenib exerts an anti-keloid activity by antagonizing TGF-β/Smad and MAPK/ERK signaling pathways

Wang, Wenbo, Qu, Miao, Xu, Lan, Wu, Xiaoli, Gao, Zhen, Gu, Tingyu, Zhang, Wenjie, Ding, Xiaoyan, Liu, Wei, Chen, Yue-Lei

Journal:

Journal of Molecular Medicine

Year:

2016

Language:

english

File:

PDF, 7.78 MB

english, 2016

30

ChemInform Abstract: (N,N-Diisopropylcarbamoyloxy)-methyl p-Tolyl Sulfone: Preparation and Application for the Syntheses of 1,2-Diols.

Ma, Lu, Zhao, Dongmei, Chen, Lin, Wang, Xin, Chen, Yue-Lei, Shen, Jingkang

Journal:

Year:

2013

File:

PDF, 39 KB

2013

31

Effects of Antitumor Drug Sorafenib on Chick Embryo Development

Cheng, Yi-Sen, Wang, Xiao-Yu, Wang, Guang, Li, Yan, Chen, Yue-Lei, Chuai, Man-li, Lee, Kenneth Ka Ho, Ding, Xiao-Yan, Yang, Xue-song

Journal:

The Anatomical Record

Year:

2015

Language:

english

File:

PDF, 977 KB

english, 2015

32

Design and synthesis of benzylpiperidine inhibitors targeting the menin–MLL1 interface

Ren, Jing, Xu, Wei, Tang, Le, Su, Minbo, Chen, Danqi, Chen, Yue-Lei, Zang, Yi, Li, Jia, Shen, Jingkang, Zhou, Yubo, Xiong, Bing

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 2.13 MB

english, 2016

33

Stereoselective and Regioselective Preparations of C-Pentopyranosides and Formal Synthesis of Omarigliptin

Liu, Tongchao, Hou, Jian, Xie, Wuchen, Li, You, Ren, Huanming, Liang, Jianpeng, Xiong, Bing, Chen, Guohua, Cheng, Maosheng, Zhao, Dongmei, Shen, Jingkang, Chen, Yue-Lei

Journal:

European Journal of Organic Chemistry

Year:

2016

Language:

english

File:

PDF, 963 KB

english, 2016

34

Decreased extracellular pH inhibits osteogenesis through proton-sensing GPR4-mediated suppression of yes-associated protein

Tao, Shi-Cong, Gao, You-Shui, Zhu, Hong-Yi, Yin, Jun-Hui, Chen, Yi-Xuan, Zhang, Yue-Lei, Guo, Shang-Chun, Zhang, Chang-Qing

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.37 MB

english, 2016

35

A one-pot synthesis of omarigliptin and its analogues through stabilized beta -amino ketone intermediate

Li, You, Liu, Tongchao, Li, Chungang, Xiong, Bing, Zhao, Dongmei, Cheng, Maosheng, Chen, Guohua, Shen, Jingkang, Chen, Yue-Lei

Journal:

Synthetic Communications

Year:

2017

Language:

english

File:

PDF, 435 KB

english, 2017

36

Stereoselective addition of Grignard reagents to (2-methyl-5- tert -butyl)phenyl 1-thio- β - D -ribopentodialdo-1,4-furanoside derivative

Ren, Huanming, Xie, Wuchen, Xiong, Bing, Shen, Jingkang, Chen, Guohua, Chen, Yue-Lei

Journal:

Year:

2017

Language:

english

File:

PDF, 1.84 MB

english, 2017

37

Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase

Tang, Jing, Vernekar, Sanjeev Kumar V., Chen, Yue-Lei, Miller, Lena, Huber, Andrew D., Myshakina, Nataliya, Sarafianos, Stefan G., Parniak, Michael A., Wang, Zhengqiang

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.04 MB

english, 2017

38

Discovery of a series of dihydroquinoxalin-2(1 H )-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor

Hu, Jianping, Wang, Yingqing, Li, Yanlian, Xu, Lin, Cao, Danyan, Song, ShanShan, Damaneh, Mohammadali Soleimani, Wang, Xin, Meng, Tao, Chen, Yue-Lei, Shen, Jingkang, Miao, Zehong, Xiong, Bing

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 2.14 MB

english, 2017

39

Osteonecrosis of the femoral head, nonunion and potential risk factors in Pauwels grade-3 femoral neck fractures

Zhang, Yue-Lei, Chen, Song, Ai, Zi-Sheng, Gao, You-Shui, Mei, Jiong, Zhang, Chang-Qing

Journal:

Medicine (Medicine Publishing Company Ltd)

Year:

2016

Language:

english

File:

PDF, 351 KB

english, 2016

40

ω-3 free fatty acids and all-trans retinoic acid synergistically induce growth inhibition of three subtypes of breast cancer cell lines

Lin, Guangxiao, Zhu, Shenglong, Wu, Yikuan, Song, Ci, Wang, Wanjing, Zhang, Yuan, Chen, Yue-Lei, He, Zhao

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 5.90 MB

english, 2017

41

A 2-hydroxyisoquinoline-1,3-dione active site RNase H inhibitor binds in multiple modes to HIV-1 reverse transcriptase

Kirby, Karen A., Myshakina, Nataliya A., Christen, Martin T., Chen, Yue-Lei, Schmidt, Hilary A., Huber, Andrew D., Xi, Zhaoyong, Kim, Seongmi, Rao, Rohit K., Kramer, Skyler T., Yang, Qiongying, Singh,

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2017

Language:

english

File:

PDF, 2.48 MB

english, 2017

42

ChemInform Abstract: Formation of 1,3-Diazocine by Palladium Catalyzed C-H Arylation.

Tang, Le, Ren, Jing, Ma, Yuchi, Wang, Xin, Chen, Lin, Shen, Jingkang, Chen, Yue-Lei, Xiong, Bing

Journal:

Year:

2016

File:

PDF, 22 KB

2016

43

Preparation of 5′-deoxy-5′-amino-5′- C -methyl adenosine derivatives and their activity against DOT1L

Liu, Tongchao, Xie, Wuchen, Li, Cong, Ren, Huanming, Mao, Yudong, Chen, Guohua, Cheng, Maosheng, Zhao, Dongmei, Shen, Jingkang, Li, Jia, Zhou, Yubo, Xiong, Bing, Chen, Yue-Lei

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 701 KB

english, 2017

44

Ilex latifolia Thunb protects mice from HFD-induced body weight gain

Wu, Hailan, Chen, Yue-Lei, Yu, Yueyuan, Zang, Jin, Wu, Yikuan, He, Zhao

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 10.64 MB

english, 2017

45

Convenient preparation of pinometostat and related 5’-deoxy-5’-amino adenosine derivatives as well as their activity against DOT1L

Liu, Tongchao, Ren, Huanming, Li, Cong, Chen, Guohua, Cheng, Maosheng, Zhao, Dongmei, Shen, Jingkang, Li, Jia, Zhou, Yubo, Xiong, Bing, Chen, Yue-Lei

Journal:

Tetrahedron Letters

Year:

2017

Language:

english

File:

PDF, 261 KB

english, 2017

46

Efficient Syntheses of alpha- and beta-C-Nucleosides and the Origin of Anomeric Selectivity

Liu, Tongchao, Zhu, Zhengdan, Ren, Huanming, Chen, Yabin, Chen, Guohua, Cheng, Maosheng, Zhao, Dongmei, Shen, Jingkang, Zhu, Weiliang, Xiong, Bing, Chen, Yue-Lei

Journal:

Organic Chemistry Frontiers

Year:

2018

Language:

english

File:

PDF, 850 KB

english, 2018

47

Sorafenib Inhibits Epithelial-Mesenchymal Transition through an Epigenetic-Based Mechanism in Human Lung Epithelial Cells

Zhang, Juyong, Chen, Yue-Lei, Ji, Guanyu, Fang, Weiying, Gao, Zhaowei, Liu, Yi, Wang, Jun, Ding, Xiaoyan, Gao, Fei, Rishi, Arun

Journal:

Year:

2013

Language:

english

File:

PDF, 2.14 MB

english, 2013

48

[American Society of Civil Engineers 14th COTA International Conference of Transportation Professionals - Changsha, China (July 4-7, 2014)] CICTP 2014 - Analysis of the Rocket Sled Track Irregularity in Time and Frequency Domains

Chen, Shi-yu, He, Yue-lei, Li, Zai-wei

Language:

english

File:

PDF, 362 KB

english

49

Editorial (Thematic Issue:Advances in Therapeutic Glycopeptides)

Zeng, Wenbin, Chen, Yue-Lei

Journal:

Protein & Peptide Letters

Year:

2014

Language:

english

File:

PDF, 85 KB

english, 2014

50

Novel Akt activator SC-79 is a potential treatment for alcohol-induced osteonecrosis of the femoral head

Chen, Yi-Xuan, Tao, Shi-Cong, Xu, Zheng-Liang, Yin, Wen-Jing, Zhang, Yue-Lei, Yin, Jun-Hui, Gao, You-Shui, Zhang, Chang-Qing

Journal:

Year:

2017

Language:

english

File:

PDF, 16.38 MB

english, 2017